Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535917 | 0.86 | TET2 (0.50) | TDP1L3MBTL1MAPTLMNANR4A2 | |
| SCHEMBL27540270 | 0.83 | L3MBTL1 (0.52) | TDP1L3MBTL1MAPTLMNANR4A2 | |
| SCHEMBL5417535 | 0.80 | AKT1 (0.50) | MAPTLMNAALDH1A1MAPK1KMT2A | |
| SCHEMBL11094690 | 0.80 | CES1 (0.50) | TDP1L3MBTL1MAPTLMNAALDH1A1 | |
| SCHEMBL14418508 | 0.79 | LMNA (0.52) | TDP1L3MBTL1MAPTLMNANR4A2 | |
| SCHEMBL7965904 | 0.78 | CES1 (0.48) | TDP1L3MBTL1MAPTLMNAALDH1A1 | |
| SCHEMBL5702382 | 0.78 | SLC6A2 (0.54) | TDP1L3MBTL1MAPTLMNAALDH1A1 | |
| SCHEMBL1572261 | 0.78 | CYP3A4 (0.59) | TDP1L3MBTL1MAPTLMNANR4A2 | |
| SCHEMBL7649584 | 0.78 | TDP1 (0.55) | TDP1L3MBTL1MAPTLMNANR4A2 | |
| SCHEMBL10473788 | 0.78 | CYP3A4 (0.59) | TDP1L3MBTL1MAPTLMNANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200385-A | Comprising leuco dye, color developer and water soluble alkylphosphate lubricants; antifogging, smoothness | RICOH COMPANY, LTD. (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5126486-A | Color developers for leuco dyes in thermal printing | RICOH COMPANY, LTD. (JP) | 1992-06-30 | — | — | US | disclosed |
| US-4978651-A | With a colorless or light colored leuco dye for inducing color formation | RICOH COMPANY, LTD. (JP) | 1990-12-18 | — | — | US | disclosed |