Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790734 | 0.96 | TSHR (0.47) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL1371273 | 0.83 | MMP8 (0.50) | NPC1SMN1; SMN2LMNATSHRCYP3A4 | |
| SCHEMBL29024336 | 0.82 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL28277988 | 0.80 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL11361667 | 0.79 | HCAR2 (0.45) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL18915623 | 0.79 | ALDH1A1 (0.54) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL28368000 | 0.79 | TSHR (0.51) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL805586 | 0.79 | KDM4E (0.58) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL5892157 | 0.79 | TSHR (0.51) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL28555860 | 0.79 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5155847-A | — | — | None | — | — | JP | claimed |
| JP-5155847-A | — | — | None | — | — | JP | disclosed |