Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562898 | 0.80 | NPC1 (0.45) | NPC1RAB9ACYP1A2KDM4EMEN1 | |
| SCHEMBL12385418 | 0.77 | MEN1 (0.44) | KDM4EMEN1KMT2AALDH1A1PRNP | |
| SCHEMBL9565589 | 0.76 | MAPT (0.42) | NPC1RAB9ACYP1A2CYP2A6KDM4E | |
| SCHEMBL19454862 | 0.72 | NPC1 (0.59) | NPC1RAB9ACYP1A2CYP2A6KDM4E | |
| SCHEMBL29531434 | 0.72 | NPC1 (0.59) | NPC1RAB9ACYP1A2CYP2A6KDM4E | |
| SCHEMBL27253072 | 0.72 | NPC1 (0.51) | NPC1RAB9ACYP1A2CYP2A6KDM4E | |
| SCHEMBL3235397 | 0.70 | ALDH1A1 (0.50) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL26350955 | 0.69 | NPC1 (0.56) | NPC1RAB9ACYP1A2CYP2A6 | |
| SCHEMBL30179132 | 0.69 | NPC1 (0.69) | NPC1RAB9ACYP1A2CYP2A6KDM4E | |
| SCHEMBL483742 | 0.69 | NPC1 (0.69) | NPC1RAB9ACYP1A2CYP2A6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543263-A2 | Benziimidazoles, pharmaceuticals containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-05-26 | — | — | EP | disclosed |