Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11976472 | 0.78 | CYP2A6 (0.52) | MAPTKDM4EKMT2ANPC1RAB9A | |
| SCHEMBL9562909 | 0.76 | NPC1 (0.46) | MAPTKDM4EKMT2ANPC1RAB9A | |
| SCHEMBL12385418 | 0.75 | MEN1 (0.44) | MAPTKDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL9562898 | 0.75 | NPC1 (0.45) | MAPTKDM4EKMT2ANPC1RAB9A | |
| SCHEMBL11976477 | 0.74 | CYP2A6 (0.50) | MAPTKDM4EKMT2ANPC1RAB9A | |
| SCHEMBL30360258 | 0.74 | CYP2A6 (0.53) | MAPTKDM4EKMT2ANPC1RAB9A | |
| SCHEMBL5468265 | 0.74 | CYP2A6 (0.53) | MAPTKDM4EKMT2ANPC1RAB9A | |
| SCHEMBL4439497 | 0.74 | CYP2A6 (0.53) | MAPTKDM4EKMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6007561 | 0.72 | CYP2A6 (0.52) | MAPTKDM4EKMT2ANPC1RAB9A | |
| SCHEMBL30011331 | 0.72 | CYP2A6 (0.52) | MAPTKDM4EKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543263-A2 | Benziimidazoles, pharmaceuticals containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-05-26 | — | — | EP | disclosed |