Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 14/20 | 0.73 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436128 | 0.88 | LTA4H (0.69) | LTA4HGRM4 | |
| SCHEMBL24032787 | 0.86 | LTA4H (0.75) | LTA4HSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3192017 | 0.86 | LTA4H (0.75) | LTA4HSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3503714 | 0.86 | LTA4H (0.75) | LTA4HSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3503717 | 0.86 | LTA4H (0.75) | LTA4HSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL29398310 | 0.86 | LTA4H (0.75) | LTA4HSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10436152 | 0.85 | LTA4H (0.66) | LTA4HSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL176813 | 0.85 | LTA4H (0.91) | LTA4HSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2522620 | 0.85 | LTA4H (0.91) | LTA4HSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL20238889 | 0.84 | LTA4H (1.00) | LTA4HSLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62171700-A | — | — | None | — | — | JP | disclosed |
| US-5229274-A | DNA code sequence, deacylation | MERCK & CO., INC. (US) | 1993-07-20 | — | — | US | disclosed |
| US-5104800-A | A bacillus megaterium culture product; cleavage of the aminoadipoyl side chain | MERCK & CO., INC. (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0405846-A1 | One-step cephalosporin C amidase enzyme, a gene encoding the same, and expression thereof in a suitable host | MERCK & CO. INC. (US) | 1991-01-02 | — | — | EP | disclosed |
| JP-S62171700-A | SUBSTRATE FOR DETERMINATION GAMMA-GLUTAMYLTANSPEPTIDASE | SHINOTESUTO KENKYUSHO:KK | 1987-07-28 | — | — | JP | disclosed |