Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | MC4R | P32245 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | MC3R | P41968 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.57 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556324 | 0.83 | KDM4E (0.61) | TSHRADORA3MC4RADRA1AMC3R | |
| SCHEMBL875263 | 0.83 | KDM4E (0.61) | TSHRADORA3MC4RADRA1AMC3R | |
| SCHEMBL11779790 | 0.81 | KDM4E (0.59) | TSHRADORA3MC4RADRA1AMC3R | |
| SCHEMBL28344838 | 0.80 | TSHR (0.62) | TSHRADORA3MC4RADRA1AMC3R | |
| SCHEMBL29651938 | 0.79 | KDM4E (0.57) | TSHRADORA3MC4RADRA1AMC3R | |
| SCHEMBL108950 | 0.79 | KDM4E (0.57) | TSHRADORA3MC4RADRA1AMC3R | |
| SCHEMBL25930231 | 0.79 | KDM4E (0.57) | TSHRADORA3MC4RADRA1AMC3R | |
| SCHEMBL1505691 | 0.79 | KDM4E (0.57) | TSHRADORA3MC4RADRA1AMC3R | |
| SCHEMBL1478640 | 0.79 | KDM4E (0.57) | TSHRADORA3MC4RADRA1AMC3R | |
| Hydrochloric Acid SCHEMBL30529579 | 0.78 | KDM4E (0.55) | TSHRADORA3MC4RADRA1AMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106866553-A | A kind of synthetic method of Favipiravir | 中南大学 | 2017-06-20 | — | — | CN | claimed |
| CN-106866553-A | A kind of synthetic method of Favipiravir | 中南大学 | 2017-06-20 | — | — | CN | disclosed |
| CN-102605356-B | Plating catalyst and method | ROHM & HAAS ELECT MAT | 2014-11-19 | — | — | CN | disclosed |
| CN-104066735-A | Substituted imidazopyrazines as AKT kinase inhibitors | BAYER IP GMBH | 2014-09-24 | — | — | CN | disclosed |
| CN-102159650-B | Conductive polymer solution, conductive coating film and input device | SHINETSU POLYMER CO | 2014-08-27 | — | — | CN | disclosed |
| CN-103827163-A | Resin having fluorene structure and underlayer film forming material for lithography | MITSUBISHI GAS CHEMICAL CO | 2014-05-28 | — | — | CN | disclosed |
| CN-103733136-A | Underlayer film forming material for lithography, underlayer film for lithography, and pattern forming method | MITSUBISHI GAS CHEMICAL CO | 2014-04-16 | — | — | CN | disclosed |
| CN-103619892-A | Phenolic resin and underlayer film forming material for lithography | MITSUBISHI GAS CHEMICAL CO | 2014-03-05 | — | — | CN | disclosed |
| CN-102036961-B | Pyridine and pyrazine compounds as PI3K inhibitors | NOVARTIS AG | 2014-02-26 | — | — | CN | disclosed |
| CN-103588704-A | Inhibitors of focal adhesion kinase | SCRIPPS RESEARCH INST | 2014-02-19 | — | — | CN | disclosed |
| CN-101316844-A | Inhibitors of diacylglycerol acyltransferase (DGAT) | HOFFMANN LA ROCHE (CH) | 2008-12-03 | — | — | CN | disclosed |
| EP-0537937-A2 | Substituted pyrazino 2,3-D pyrimidinones as angiotensin II antagonists | MERCK & CO. INC. (US) | 1993-04-21 | — | — | EP | disclosed |