Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | MC4R | P32245 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | MC3R | P41968 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29651938 | 1.00 | KDM4E (0.57) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| Hydrochloric Acid SCHEMBL29070148 | 0.98 | KDM4E (0.55) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| Hydrochloric Acid SCHEMBL30529579 | 0.98 | KDM4E (0.55) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| Hydrochloric Acid SCHEMBL27902568 | 0.98 | KDM4E (0.55) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL2649965 | 0.93 | RAB9A (0.52) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| Trifluoroacetic Acid SCHEMBL31010384 | 0.88 | KDM4E (0.50) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL29556324 | 0.83 | KDM4E (0.61) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL875263 | 0.83 | KDM4E (0.61) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL3971624 | 0.82 | ALDH1A1 (0.45) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| Dimethylamine SCHEMBL4392114 | 0.81 | KDM4E (0.50) | KDM4ENAPRTHCAR2TSHRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 713 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110372681-B | Application of self-assembled nano fluorescent probe for selectively detecting human serum albumin | 天津医科大学 | 2022-06-07 | — | — | CN | claimed |
| US-20210206752-A1 | METHODS FOR PREPARING OLTIPRAZ | SUPPORTIVE THERAPEUTICS AG (CH) | 2021-07-08 | — | — | US | claimed |
| US-10968207-B2 | Methods for preparing oltipraz | ST IP HOLDING AG (CH) | 2021-04-06 | — | — | US | claimed |
| US-20200247791-A1 | METHODS FOR PREPARING OLTIPRAZ | ST IP HOLDING AG (CH) | 2020-08-06 | — | — | US | claimed |
| US-20200172522-A1 | METHODS FOR PREPARING OLTIPRAZ | SUPPORTIVE THERAPEUTICS AG (CH) | 2020-06-04 | — | — | US | claimed |
| CN-110372681-A | A kind of application of the self-assembled nanometer fluorescence probe for selective enumeration method human serum albumins | 天津医科大学 | 2019-10-25 | — | — | CN | claimed |
| US-20190084971-A1 | METHODS FOR PREPARING OLTIPRAZ | ST IP HOLDING AG (CH) | 2019-03-21 | — | — | US | claimed |
| CN-108067191-A | For the reactor assembly of orthophosphates in Adsorption waste water | 北京益清源环保科技有限公司 | 2018-05-25 | — | — | CN | claimed |
| WO-2018078657-A1 | PROCESS FOR PREPARATION OF GLIPIZIDE | J.B. CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2018-05-03 | — | — | WO | claimed |
| US-20170012208-A1 | ORGANIC SEMICONDUCTOR FORMULATIONS | USINVEST LLC | 2017-01-12 | — | — | US | claimed |
| CN-1717406-A | Method for preparing Oltipraz | CJ CORP (KR) | 2006-01-04 | — | — | CN | claimed |
| EP-1565460-A1 | METHOD FOR PREPARING OLTIPRAZ | CJ Corporation (KR) | 2005-08-24 | — | — | EP | claimed |
| US-20050004178-A1 | Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders | ARENA PHARMACEUTICALS, INC. (US) | 2005-01-06 | — | — | US | claimed |
| US-20040142377-A1 | Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders | ARENA PHARMACEUTICALS, INC. (US) | 2004-07-22 | — | — | US | claimed |
| WO-2004048369-A1 | METHOD FOR PREPARING OLTIPRAZ | CJ CORPORATION (KR) | 2004-06-10 | — | — | WO | claimed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
| US-4957640-A | Corrosion prevention with compositions prepared from organic fatty amines and nitrogen-containing aromatic heterocyclic compounds | THE DOW CHEMICAL COMPANY (US) | 1990-09-18 | — | — | US | claimed |
| US-4076537-A | Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers | FUJI PHOTO FILM CO., LTD. (JA) | 1978-02-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968207-B2 | Methods for preparing oltipraz | CYP51A1, UGT1A3, UGT1A4 | KDM4E 704/4885NAPRT 1271/4885HCAR2 3116/4885 |
| US-20210206752-A1 | METHODS FOR PREPARING OLTIPRAZ | CYP51A1, UGT1A3, UGT1A4 | KDM4E 704/4885NAPRT 1271/4885HCAR2 3116/4885 |
| US-20200172522-A1 | METHODS FOR PREPARING OLTIPRAZ | CYP51A1, UGT1A3, UGT1A4 | KDM4E 704/4885NAPRT 1271/4885HCAR2 3116/4885 |
| US-20190084971-A1 | METHODS FOR PREPARING OLTIPRAZ | CYP51A1, UGT1A3, UGT1A4 | KDM4E 704/4885NAPRT 1271/4885HCAR2 3116/4885 |
| US-20050004178-A1 | Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders | GPR119, ADIPOR2, GCGR | KDM4E 3486/4885NAPRT 477/4885HCAR2 41/4885 |
| US-20040142377-A1 | Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders | GPR119, ADIPOR2, GCGR | KDM4E 3486/4885NAPRT 477/4885HCAR2 41/4885 |
| US-20200247791-A1 | METHODS FOR PREPARING OLTIPRAZ | CYP51A1, UGT1A3, UGT1A4 | KDM4E 704/4885NAPRT 1271/4885HCAR2 3116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.