SCHEMBL875263

SCHEMBL875263

O=C(OC(=O)c1cnccn1)c1cnccn1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.61
NAPRT Q6XQN6 1/20 0.61
HCAR2 Q8TDS4 1/20 0.61
TSHR P16473 4/20 0.59
ADORA3 P0DMS8 1/20 0.59
MC4R P32245 1/20 0.59
ADRA1A P35348 1/20 0.59
MC3R P41968 1/20 0.59
MAPT P10636 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
POLB P06746 4/20 0.51
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
RECQL P46063 1/20 0.49
BAZ2B Q9UIF8 1/20 0.48
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
ALDH1A1 P00352 1/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29556324 1.00 KDM4E (0.61) KDM4ENAPRTHCAR2TSHRADORA3
SCHEMBL16328267 0.88 KDM4E (0.53) KDM4ENAPRTHCAR2TSHRADORA3
SCHEMBL28344838 0.88 TSHR (0.62) KDM4ENAPRTHCAR2TSHRADORA3
SCHEMBL8345410 0.87 CES2 (0.50) KDM4ENAPRTHCAR2TSHRADORA3
SCHEMBL11779790 0.84 KDM4E (0.59) KDM4ENAPRTHCAR2TSHRADORA3
SCHEMBL9616232 0.84 TSHR (0.49) KDM4ENAPRTHCAR2TSHRADORA3
SCHEMBL28697246 0.83 KDM4E (0.48) KDM4ENAPRTHCAR2TSHRADORA3
SCHEMBL1505691 0.83 KDM4E (0.57) KDM4ENAPRTHCAR2TSHRADORA3
SCHEMBL9563007 0.83 TSHR (0.61) KDM4ENAPRTHCAR2TSHRADORA3
SCHEMBL29651938 0.83 KDM4E (0.57) KDM4ENAPRTHCAR2TSHRADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-213133193-U A concentrated solution accepts cauldron for production of pyrazine carboxylic anhydride 江西省益丰化工有限公司 2021-05-07 CN claimed
CN-213141456-U Waste water desalination device for pyrazine carboxylic anhydride production capable of recovering waste heat 江西省益丰化工有限公司 2021-05-07 CN claimed
CN-213132724-U Quantitative-feeding mixing machine for pyrazine carboxylic anhydride production 江西省益丰化工有限公司 2021-05-07 CN claimed
CN-213133189-U Pyrazine carboxylic anhydride oxidation reaction kettle capable of quickly collecting filtrate 江西省益丰化工有限公司 2021-05-07 CN claimed
CN-213102199-U Pyrazine carboxylic anhydride production is with transferring sour bucket convenient to ration unloading 江西省益丰化工有限公司 2021-05-04 CN claimed
CN-213102212-U A oxidation reation kettle for production of pyrazine carboxylic anhydride 江西省益丰化工有限公司 2021-05-04 CN claimed
CN-213101572-U Tail gas absorption tower is used in preparation of pyrazine carboxylic anhydride 江西省益丰化工有限公司 2021-05-04 CN claimed
CN-213102200-U Water receiving tank convenient for adjusting internal space and used for pyrazine carboxylic anhydride production 江西省益丰化工有限公司 2021-05-04 CN claimed
CN-213101090-U Pyrazine carboxylic anhydride production water metering tank 江西省益丰化工有限公司 2021-05-04 CN claimed
CN-212954373-U Waste water collection kettle for pyrazine carboxylic anhydride production 江西省益丰化工有限公司 2021-04-13 CN claimed
CN-212962553-U Sustainable turn-over drying device for pyrazine carboxylic anhydride production 江西省益丰化工有限公司 2021-04-13 CN claimed
US-4957640-A Corrosion prevention with compositions prepared from organic fatty amines and nitrogen-containing aromatic heterocyclic compounds THE DOW CHEMICAL COMPANY (US) 1990-09-18 US claimed
US-4765839-A PAVING THE DOW CHEMICAL COMPANY (US) 1988-08-23 US claimed
CN-114442431-A Photosensitive resin composition containing polyimide precursor 上海玟昕科技有限公司 2022-05-06 CN disclosed
CN-114415472-A Photosensitive resin composition containing polyimide precursor 上海玟昕科技有限公司 2022-04-29 CN disclosed
CN-213133189-U Pyrazine carboxylic anhydride oxidation reaction kettle capable of quickly collecting filtrate 江西省益丰化工有限公司 2021-05-07 CN disclosed
EP-0296560-A2 1,4-Substituted piperidines as acetylcholinesterase inhibitors and their use for the treatment of Alzheimer's disease Eisai Co., Ltd. (JP) 1988-12-28 EP disclosed
US-4765839-A PAVING THE DOW CHEMICAL COMPANY (US) 1988-08-23 US disclosed
US-4761473-A CORROSION RESISTANCE OF OIL OR GAS WELLS THE DOW CHEMICAL COMPANY (US) 1988-08-02 US disclosed
US-4311843-A Di-n-alkyl dicarboxypyrazinedicarboxylates and ferrous complexes WILEY RICHARD H 1982-01-19 US disclosed