Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 9/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563416 | 0.91 | PARP14 (0.46) | PARP14BCHEHPGDSOPRM1OPRD1 | |
| SCHEMBL9563307 | 0.90 | PARP14 (0.52) | PARP14BCHEHPGDSFAAHOPRM1 | |
| SCHEMBL9563295 | 0.90 | PARP14 (0.50) | PARP14BCHEHPGDSOPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL9563234 | 0.90 | PARP14 (0.45) | PARP14BCHEHPGDSOPRM1OPRD1 | |
| SCHEMBL9563175 | 0.86 | PARP14 (0.42) | PARP14BCHEHPGDSHTR1A | |
| SCHEMBL9563325 | 0.86 | CYP2D6 (0.46) | PARP14BCHEHPGDSNPC1HTT | |
| SCHEMBL9563340 | 0.84 | HTR1A (0.40) | PARP14BCHEHPGDSOPRM1OPRD1 | |
| SCHEMBL9563200 | 0.83 | PARP14 (0.40) | PARP14BCHEHPGDSOPRM1OPRD1 | |
| SCHEMBL9563357 | 0.81 | PARP14 (0.55) | PARP14BCHEHPGDSOPRM1NPC1 | |
| SCHEMBL9563205 | 0.81 | PARP14 (0.58) | PARP14BCHEHPGDSOPRM1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |