Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 7/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563304 | 0.92 | BCHE (0.41) | HTR1AHTR7PARP14BCHECHRM3 | |
| SCHEMBL9565887 | 0.91 | BCHE (0.45) | HTR1APARP14BCHECHRM3ADRB2 | |
| SCHEMBL9563305 | 0.91 | PARP14 (0.47) | HTR1AHTR7PARP14BCHECHRM3 | |
| SCHEMBL9563256 | 0.88 | HTR1A (0.40) | HTR1AHTR7PARP14BCHECHRM3 | |
| SCHEMBL9563260 | 0.85 | CHRM3 (0.39) | HTR1AHTR7PARP14BCHECHRM3 | |
| SCHEMBL9563171 | 0.84 | PARP14 (0.43) | HTR1APARP14BCHECHRM3OPRM1 | |
| SCHEMBL9563384 | 0.84 | PARP14 (0.49) | HTR1APARP14BCHECHRM3ADRB2 | |
| SCHEMBL9563263 | 0.84 | BCHE (0.52) | HTR1APARP14BCHECHRM3MEN1 | |
| Hydrochloric Acid SCHEMBL9563254 | 0.83 | BCHE (0.51) | HTR1APARP14BCHECHRM3MEN1 | |
| SCHEMBL9563325 | 0.82 | CYP2D6 (0.46) | PARP14BCHEALDH1A1HPGDSNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |