Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563231 | 0.89 | DRD4 (0.37) | SLC6A2CYP2D6HTR1ADRD4TSHR | |
| SCHEMBL9563225 | 0.85 | HTR1A (0.48) | SLC6A2CYP2D6CHRM2HTR1AADRA2A | |
| SCHEMBL9563263 | 0.84 | BCHE (0.52) | SLC6A2CYP2D6CHRM2HTR1AADRA2A | |
| SCHEMBL9563179 | 0.83 | BCHE (0.56) | SLC6A2CYP2D6CHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL9563254 | 0.83 | BCHE (0.51) | SLC6A2CYP2D6CHRM2HTR1AADRA2A | |
| SCHEMBL9563339 | 0.83 | BCHE (0.55) | SLC6A2CYP2D6CHRM2HTR1AADRA2A | |
| SCHEMBL9563380 | 0.82 | GRM5 (0.42) | SLC6A2CYP2D6CHRM2HTR1AADRA2A | |
| SCHEMBL9563193 | 0.82 | GRM5 (0.42) | SLC6A2CYP2D6CHRM2HTR1AADRA2A | |
| SCHEMBL9563328 | 0.82 | SLC6A2 (0.42) | SLC6A2CYP2D6CHRM2HTR1AADRA2A | |
| SCHEMBL9563195 | 0.82 | GRM5 (0.42) | SLC6A2CYP2D6CHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |