Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563232 | 0.89 | SLC6A2 (0.43) | DRD4TSHRL3MBTL1PRMT5ADRB2 | |
| SCHEMBL9563304 | 0.86 | BCHE (0.41) | DRD4ADRB2ADRB3ADRB1CHRM3 | |
| SCHEMBL9565887 | 0.84 | BCHE (0.45) | DRD4TSHRADRB2ADRB3ADRB1 | |
| SCHEMBL9563258 | 0.84 | PRMT5 (0.34) | TSHRPRMT5ADRB2ADRB3CHRM3 | |
| SCHEMBL9563249 | 0.84 | PRMT5 (0.34) | TSHRPRMT5ADRB2ADRB3CHRM3 | |
| SCHEMBL9563351 | 0.84 | PRMT5 (0.34) | TSHRPRMT5ADRB2ADRB3CHRM3 | |
| SCHEMBL9563250 | 0.83 | SCN8A (0.36) | TSHRPRMT5ADRB3HTR1ASIGMAR1 | |
| SCHEMBL9563190 | 0.83 | TSHR (0.41) | DRD4TSHRL3MBTL1HTR1AGRM5 | |
| SCHEMBL9563210 | 0.81 | L3MBTL1 (0.48) | DRD4TSHRL3MBTL1HRH1CYP2D6 | |
| SCHEMBL9563260 | 0.79 | CHRM3 (0.39) | ADRB2CHRM3HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |