Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563201 | 1.00 | SLC6A3 (0.34) | SLC6A3HTR1ADRD3CHRM2ADRA2A | |
| SCHEMBL9563196 | 1.00 | SLC6A3 (0.34) | SLC6A3HTR1ADRD3CHRM2ADRA2A | |
| SCHEMBL9563243 | 0.88 | CYP2D6 (0.46) | SLC6A3HTR1ADRD3CHRM2ADRA2A | |
| SCHEMBL9563248 | 0.88 | CYP2D6 (0.46) | SLC6A3HTR1ADRD3CHRM2ADRA2A | |
| SCHEMBL9563240 | 0.88 | CYP2D6 (0.46) | SLC6A3HTR1ADRD3CHRM2ADRA2A | |
| SCHEMBL9563293 | 0.84 | RAB9A (0.39) | CYP2D6BCHE | |
| SCHEMBL9563287 | 0.84 | RAB9A (0.39) | CYP2D6BCHE | |
| SCHEMBL9563382 | 0.84 | RAB9A (0.39) | CYP2D6BCHE | |
| SCHEMBL9563416 | 0.83 | PARP14 (0.46) | SLC6A3HTR1ADRD3CHRM2ADRA2A | |
| SCHEMBL9563351 | 0.82 | PRMT5 (0.34) | SLC6A3HTR1ADRD3CHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |