Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.59 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563205 | 0.94 | PARP14 (0.58) | BCHEPARP14CYP2D6DRD3DRD2 | |
| SCHEMBL9563358 | 0.90 | BCHE (0.61) | BCHEPARP14CYP2D6DRD3DRD2 | |
| SCHEMBL9563292 | 0.90 | PARP14 (0.52) | BCHEPARP14CYP2D6DRD3DRD2 | |
| SCHEMBL9563228 | 0.89 | BCHE (0.60) | BCHEPARP14CYP2D6DRD3DRD2 | |
| SCHEMBL9563188 | 0.88 | DRD2 (0.53) | BCHEPARP14CYP2D6DRD2LMNA | |
| SCHEMBL9563310 | 0.88 | BCHE (0.57) | BCHEPARP14MEN1MAPTKMT2A | |
| SCHEMBL9563194 | 0.88 | DRD1 (0.53) | BCHEPARP14CYP2D6DRD3DRD2 | |
| SCHEMBL9563277 | 0.88 | PARP14 (0.48) | BCHEPARP14MAPTCYP2D6DRD3 | |
| SCHEMBL9563306 | 0.88 | PARP14 (0.51) | BCHEPARP14CYP2D6DRD3DRD2 | |
| SCHEMBL9563357 | 0.88 | PARP14 (0.55) | BCHEPARP14CYP2D6DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |