Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563245 | 0.92 | PARP14 (0.51) | DRD2BCHEPARP14LMNACHRM2 | |
| SCHEMBL9563253 | 0.88 | BCHE (0.59) | DRD2BCHEPARP14LMNACHRM2 | |
| SCHEMBL9563268 | 0.85 | DRD2 (0.50) | DRD2BCHEPARP14CYP2D6CYP2C19 | |
| SCHEMBL12090256 | 0.84 | DRD2 (0.49) | DRD2BCHELMNACHRM2ADRA2B | |
| SCHEMBL9532269 | 0.84 | DRD2 (0.51) | DRD2BCHELMNACHRM2ADRA2B | |
| SCHEMBL9531438 | 0.83 | BCHE (0.53) | DRD2BCHELMNACHRM2ADRA2B | |
| SCHEMBL9557473 | 0.83 | DRD2 (0.48) | DRD2BCHE | |
| SCHEMBL9532495 | 0.82 | DRD2 (0.51) | DRD2BCHELMNACHRM2ADRA2B | |
| SCHEMBL13291278 | 0.82 | BCHE (0.52) | DRD2BCHELMNACHRM2ADRA2B | |
| SCHEMBL9563205 | 0.82 | PARP14 (0.58) | DRD2BCHEPARP14LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |