SCHEMBL9563352

SCHEMBL9563352

[O]C(=O)C(F)(OC(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11547476 0.83 ALDH1A1 (0.42) ALDH1A1THRB
SCHEMBL2887903 0.81 THRB (0.41) ALDH1A1THRB
SCHEMBL236894 0.81 ALDH1A1 (0.41) ALDH1A1THRB
SCHEMBL31512502 0.81 THRB (0.41) ALDH1A1THRB
SCHEMBL20561093 0.79 ALDH1A1 (0.40) ALDH1A1THRB
SCHEMBL21065620 0.79 ALDH1A1 (0.40) ALDH1A1THRB
SCHEMBL10340015 0.79 ALDH1A1 (0.40) ALDH1A1THRB
SCHEMBL22142472 0.79 ALDH1A1 (0.40) ALDH1A1THRB
SCHEMBL10635788 0.79 ALDH1A1 (0.40) ALDH1A1THRB
Methane SCHEMBL21065618 0.79 ALDH1A1 (0.40) ALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5051527-A Liquid crystal compounds having fluoroalkyl radical SHOWA SHELL SEKIYU K.K. (JP) 1991-09-24 US claimed
EP-0331367-A2 Liquid crystal compounds having fluoroalkyl radical Showa Shell Sekiyu Kabushiki Kaisha (JP) 1989-09-06 EP claimed
EP-0331367-B1 Liquid crystal compounds having fluoroalkyl radical SHOWA SHELL SEKIYU (JP) 1993-12-08 EP disclosed
EP-0331367-A2 Liquid crystal compounds having fluoroalkyl radical Showa Shell Sekiyu Kabushiki Kaisha (JP) 1989-09-06 EP disclosed