Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 18/20 | 1.00 |
| ▸ | DDX5 | P17844 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.75 |
| ▸ | HBB | P68871 | 2/20 | 0.75 |
| ▸ | CASP1 | P29466 | 1/20 | 0.75 |
| ▸ | CASP7 | P55210 | 1/20 | 0.75 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | GLA | P06280 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | STAT6 | P42226 | 1/20 | 0.74 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.74 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.74 |
| ▸ | GMNN | O75496 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29429769 | 1.00 | TOP1 (1.00) | TOP1DDX5MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20286453 | 1.00 | TOP1 (1.00) | TOP1DDX5MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30255916 | 1.00 | TOP1 (1.00) | TOP1DDX5MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18296600 | 1.00 | TOP1 (1.00) | TOP1DDX5MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29473358 | 1.00 | TOP1 (1.00) | TOP1DDX5MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13931437 | 0.94 | TOP1 (1.00) | TOP1DDX5MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18296599 | 0.94 | TOP1 (1.00) | TOP1DDX5MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25932530 | 0.91 | TOP1 (0.84) | TOP1DDX5MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6786007 | 0.89 | TOP1 (0.80) | TOP1DDX5MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15342071 | 0.89 | TOP1 (0.80) | TOP1DDX5MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026103680-A1 | BISPECIFIC ANTIBODY-MULTIPLE-PAYLOAD CONJUGATE | 江苏康宁杰瑞生物制药有限公司 | 2026-05-21 | — | — | WO | disclosed |
| WO-2026103681-A1 | PROTEIN-GLYCAN CONJUGATE HAVING MULTIPLE PAYLOADS | 江苏康宁杰瑞生物制药有限公司 | 2026-05-21 | — | — | WO | disclosed |
| CN-116178699-B | Drug delivery carrier material capable of promoting drug to enter cells, and preparation method and application thereof | 浙江大学医学院附属第一医院 | 2024-12-03 | — | — | CN | disclosed |
| CN-118203667-A | Application of DDX5 inhibitor in preparation of novel coronavirus inhibitor | 中国人民解放军军事科学院军事医学研究院 | 2024-06-18 | — | — | CN | disclosed |
| US-20230270867-A1 | CONJUGATE IN WHICH FL118 DRUG IS LINKED TO ACID-SENSITIVE LINKER, AND IMMUNOCONJUGATE USING SAME | PINOTBIO, INC. (KR) | 2023-08-31 | — | — | US | disclosed |
| US-20230270867-A1 | CONJUGATE IN WHICH FL118 DRUG IS LINKED TO ACID-SENSITIVE LINKER, AND IMMUNOCONJUGATE USING SAME | PINOTBIO, INC. (KR) | 2023-08-31 | — | — | US | disclosed |
| CN-116178699-A | Drug delivery carrier material capable of promoting drug to enter cells, and preparation method and application thereof | 浙江大学医学院附属第一医院 | 2023-05-30 | — | — | CN | disclosed |
| US-10400064-B2 | Glycerol-based polycarbonates | TRUSTEES OF BOSTON UNIVERSITY (US) | 2019-09-03 | — | — | US | disclosed |
| CN-108778340-A | Include the therapeutic nanoparticle and its preparation and application of therapeutic agent | 辉瑞公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-108697815-A | Therapeutic nano particle and its preparation and application with EGFR ligands | 辉瑞公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-107811971-A | Liposome for drug delivery | 益普生生物制药公司 | 2018-03-20 | — | — | CN | disclosed |
| CN-103948545-B | Liposome for drug delivery | 益普生生物制药公司 | 2017-10-03 | — | — | CN | disclosed |
| CN-101646449-A | Be used for the treatment of compositions and method with cancer diagnosis | SQUICOR US | 2010-02-10 | — | — | CN | disclosed |
| EP-0556585-A2 | Condensed camptothecin derivatives their production and use as antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-08-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10400064-B2 | Glycerol-based polycarbonates | GK, AGPAT5, PC | TOP1 476/4885DDX5 3887/4885MEN1 3696/4885 |
| US-20230270867-A1 | CONJUGATE IN WHICH FL118 DRUG IS LINKED TO ACID-SENSITIVE LINKER, AND IMMUNOCONJUGATE USING SAME | SLC46A1, SLC47A1, FOLR1 | TOP1 988/4885DDX5 4343/4885MEN1 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.