Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | AHCY | P23526 | 4/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.47 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563452 | 0.86 | FDPS (0.61) | FGFR1SLC22A6CYP3A4 | |
| SCHEMBL9563449 | 0.81 | HPRT1 (0.63) | — | |
| SCHEMBL9563495 | 0.80 | HDAC6 (0.44) | — | |
| SCHEMBL9563463 | 0.78 | ADORA2A (0.50) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL9569748 | 0.76 | FGFR1 (0.55) | FGFR1SLC22A6ADORA2AADORA1CYP3A4 | |
| SCHEMBL9569751 | 0.76 | FGFR1 (0.55) | FGFR1SLC22A6ADORA2AADORA1CYP3A4 | |
| SCHEMBL9569755 | 0.76 | FGFR1 (0.55) | FGFR1SLC22A6ADORA2AADORA1CYP3A4 | |
| SCHEMBL28742775 | 0.75 | FGFR1 (0.65) | FGFR1SLC22A6ADORA2AADORA1CYP3A4 | |
| SCHEMBL29353118 | 0.74 | ADORA2A (0.66) | FGFR1SLC22A6ADORA2AADORA1CYP3A4 | |
| SCHEMBL10670033 | 0.74 | FGFR1 (0.65) | FGFR1SLC22A6ADORA2AADORA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531597-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |