Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 10/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 9/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563451 | 0.86 | FGFR1 (0.57) | FGFR1SLC22A6CYP3A4 | |
| SCHEMBL9563495 | 0.84 | HDAC6 (0.44) | FDPSHDAC6P2RY1 | |
| SCHEMBL9563449 | 0.79 | HPRT1 (0.63) | HPRT1 | |
| SCHEMBL9563454 | 0.78 | FDPS (0.47) | FDPSHDAC6P2RX7P2RY1FGFR1 | |
| SCHEMBL3983260 | 0.76 | FDPS (1.00) | FDPSHDAC6P2RX7P2RY1FGFR1 | |
| SCHEMBL9741153 | 0.70 | ADORA2A (0.66) | FDPSHDAC6P2RX7FGFR1FGFR4 | |
| SCHEMBL23323404 | 0.70 | FDPS (0.63) | FDPSHDAC6P2RX7FGFR1FGFR4 | |
| SCHEMBL15453261 | 0.69 | FDPS (0.52) | FDPSHDAC6P2RX7FGFR1FGFR4 | |
| SCHEMBL9563511 | 0.69 | AMPD2 (0.30) | — | |
| SCHEMBL11596393 | 0.68 | FDPS (0.54) | FDPSHDAC6P2RX7FGFR1FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531597-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |