Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.60 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.56 |
| ▸ | ADCY5 | O95622 | 4/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | AHCY | P23526 | 3/20 | 0.51 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.48 |
| ▸ | PI4KA | P42356 | 1/20 | 0.48 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.48 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9295987 | 0.93 | ADORA2A (0.61) | ADORA2AFGFR1SLC22A6ADORA1ADCY5 | |
| SCHEMBL9295999 | 0.93 | ADORA2A (0.61) | ADORA2AFGFR1SLC22A6ADORA1ADCY5 | |
| SCHEMBL29353118 | 0.80 | ADORA2A (0.66) | ADORA2AFGFR1SLC22A6ADORA1ADCY5 | |
| SCHEMBL9569621 | 0.80 | ENPP1 (0.59) | ADORA2AFGFR1SLC22A6ADORA1AHCY | |
| SCHEMBL9569556 | 0.80 | ENPP1 (0.59) | ADORA2AFGFR1SLC22A6ADORA1AHCY | |
| SCHEMBL9569755 | 0.79 | FGFR1 (0.55) | ADORA2AFGFR1SLC22A6ADORA1ADCY5 | |
| SCHEMBL9569751 | 0.79 | FGFR1 (0.55) | ADORA2AFGFR1SLC22A6ADORA1ADCY5 | |
| SCHEMBL9569748 | 0.79 | FGFR1 (0.55) | ADORA2AFGFR1SLC22A6ADORA1ADCY5 | |
| SCHEMBL9563438 | 0.79 | HDAC6 (0.47) | HPRT1 | |
| SCHEMBL9563459 | 0.78 | ADORA2A (0.60) | ADORA2AFGFR1SLC22A6ADORA1ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | claimed |
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| EP-0531597-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |