Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | ADCY5 | O95622 | 4/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | AHCY | P23526 | 2/20 | 0.48 |
| ▸ | PI4KA | P42356 | 1/20 | 0.48 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.48 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 3/20 | 0.46 |
| ▸ | NSD3 | Q9BZ95 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563440 | 0.79 | HSP90AB1 (0.44) | — | |
| SCHEMBL9563456 | 0.78 | ADORA2A (0.60) | ADORA2AADORA1ADORA2BADCY5FGFR1 | |
| SCHEMBL9569459 | 0.78 | ADORA2A (0.71) | ADORA2AADORA1ADORA2BADCY5AHCY | |
| SCHEMBL9563504 | 0.78 | ADORA2A (0.83) | ADORA2AADORA1ADORA2BADCY5AHCY | |
| SCHEMBL9563514 | 0.77 | TK1 (0.61) | — | |
| SCHEMBL1074972 | 0.76 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADCY5AHCY | |
| SCHEMBL454185 | 0.76 | ADORA2A (0.72) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| SCHEMBL27577009 | 0.75 | ADORA2A (0.45) | ADORA2AADORA1ADORA2BFGFR1SLC22A6 | |
| SCHEMBL3288039 | 0.75 | ADORA2A (0.45) | ADORA2AADORA1ADORA2BFGFR1SLC22A6 | |
| SCHEMBL9563474 | 0.75 | LMNA (0.42) | ADORA2AADCY5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | claimed |
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| EP-0531597-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |