Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.59 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.53 |
| ▸ | AHCY | P23526 | 9/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569621 | 1.00 | ENPP1 (0.59) | ENPP1FGFR1SLC22A6NT5EAHCY | |
| SCHEMBL9569474 | 0.84 | ENPP1 (0.53) | ENPP1FGFR1SLC22A6NT5EAHCY | |
| SCHEMBL9569496 | 0.84 | ENPP1 (0.53) | ENPP1FGFR1SLC22A6NT5EAHCY | |
| SCHEMBL9295987 | 0.81 | ADORA2A (0.61) | FGFR1SLC22A6AHCYCYP3A4ADORA2A | |
| SCHEMBL9295999 | 0.81 | ADORA2A (0.61) | FGFR1SLC22A6AHCYCYP3A4ADORA2A | |
| SCHEMBL9563456 | 0.80 | ADORA2A (0.60) | FGFR1SLC22A6AHCYCYP3A4ADORA2A | |
| SCHEMBL8561474 | 0.79 | ENPP1 (0.73) | ENPP1FGFR1SLC22A6NT5ECYP3A4 | |
| SCHEMBL13648201 | 0.78 | ENPP1 (0.65) | ENPP1FGFR1SLC22A6NT5EAHCY | |
| SCHEMBL8897180 | 0.78 | SLC22A6 (0.72) | ENPP1FGFR1SLC22A6NT5EAHCY | |
| SCHEMBL9663806 | 0.77 | HPRT1 (0.68) | CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | claimed |