SCHEMBL9563549

SCHEMBL9563549

C=C[Si](C)(CCl)c1cccc(C(F)(F)F)c1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
NFE2L2 Q16236 1/20 0.36
PNMT P11086 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
ATM Q13315 1/20 0.35
IDO1 P14902 2/20 0.34
NOTUM Q6P988 3/20 0.34
IDH2 P48735 1/20 0.34
BRD4 O60885 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9563619 0.85 ALDH1A1 (0.34) HTR2AHTR2CHTR2BTSHRMAPK1
SCHEMBL9563555 0.84 ALDH1A1 (0.33) HTR2AHTR2CHTR2BTSHRMAPK1
SCHEMBL9563556 0.84 ALDH1A1 (0.33) HTR2AHTR2CHTR2BTSHRMAPK1
SCHEMBL9563602 0.84 ALDH1A1 (0.33) HTR2AHTR2CHTR2BTSHRMAPK1
SCHEMBL9563524 0.82 NR1H2 (0.41) TAAR1ALDH1A1
SCHEMBL18234156 0.79 NR1H2 (0.49) HTR2AHTR2CHTR2BTSHRMAPK1
SCHEMBL7524213 0.79 TSHR (0.41) HTR2AHTR2CHTR2BTSHRMAPK1
SCHEMBL29214115 0.79 TSHR (0.41) HTR2AHTR2CHTR2BTSHRMAPK1
SCHEMBL29214121 0.77 TSHR (0.45) HTR2AHTR2CHTR2BTSHRMAPK1
SCHEMBL29214167 0.75 TSHR (0.44) TSHRMAPK1NFE2L2PNMTTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524829-A1 Novel silane compound, process of preparing the same and plant growth regulator containing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-01-27 EP disclosed