SCHEMBL9563524

SCHEMBL9563524

C=C[Si](C)(CCl)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 6/20 0.41
NR1H3 Q13133 6/20 0.41
KIF11 P52732 2/20 0.34
TGM2 P21980 1/20 0.34
LMNA P02545 1/20 0.34
HTT P42858 1/20 0.34
AHR P35869 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
FLT3 P36888 1/20 0.32
PRKCD Q05655 1/20 0.32
CAMK2B Q13554 1/20 0.32
CAMK2G Q13555 1/20 0.32
CAMK2D Q13557 1/20 0.32
HIF1A Q16665 1/20 0.32
EPAS1 Q99814 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9563549 0.82 HTR2A (0.36) TAAR1ALDH1A1
SCHEMBL9563568 0.82 NR1H2 (0.36) NR1H2NR1H3KIF11TGM2LMNA
SCHEMBL9563529 0.81 NR1H2 (0.38) NR1H2NR1H3KIF11TGM2LMNA
SCHEMBL9563519 0.81 NR1H2 (0.36) NR1H2NR1H3LMNAHTT
SCHEMBL9563595 0.81 NR1H2 (0.36) NR1H2NR1H3LMNAHTT
SCHEMBL9563591 0.81 NR1H2 (0.36) NR1H2NR1H3LMNAHTT
SCHEMBL11316901 0.77 MAPT (0.38) ALDH1A1
SCHEMBL7523329 0.75 NR1H2 (0.42) NR1H2NR1H3KIF11LMNAHTT
SCHEMBL29214098 0.75 NR1H2 (0.47) NR1H2NR1H3KIF11TGM2ALDH1A1
SCHEMBL29214136 0.75 NR1H2 (0.47) NR1H2NR1H3KIF11TGM2AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524829-A1 Novel silane compound, process of preparing the same and plant growth regulator containing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-01-27 EP disclosed