SCHEMBL9563769

SCHEMBL9563769

CCCc1ccc(-c2ccc(-c3ccc(-c4ccc(CC)cc4)c(F)c3F)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.41
MPL P40238 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
RARB P10826 2/20 0.38
MCL1 Q07820 1/20 0.38
LPL P06858 1/20 0.37
LIPG Q9Y5X9 1/20 0.37
NISCH Q9Y2I1 1/20 0.37
MAOB P27338 1/20 0.36
LMNA P02545 1/20 0.36
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
ALOX5 P09917 1/20 0.36
NPC1 O15118 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
GFER P55789 1/20 0.36
GCGR P47871 1/20 0.35
MAPK14 Q16539 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9493621 0.98 TAAR1 (0.42) TAAR1MPLL3MBTL1RARBMCL1
SCHEMBL9563689 0.94 MCL1 (0.41) MPLRARBMCL1LPLLIPG
SCHEMBL9494063 0.92 LPL (0.42) MPLRARBMCL1LPLLIPG
SCHEMBL10535716 0.92 CTSL (0.40) TAAR1MPLL3MBTL1RARBMCL1
SCHEMBL20023225 0.91 RARB (0.40) TAAR1MPLRARBMCL1LPL
SCHEMBL20023226 0.91 RARB (0.40) TAAR1MPLRARBMCL1LPL
SCHEMBL30106830 0.91 RARB (0.40) TAAR1MPLRARBMCL1LPL
SCHEMBL20012999 0.89 RARB (0.41) TAAR1MPLRARBMCL1LPL
SCHEMBL11996379 0.89 CHKA (0.39) TAAR1MPLL3MBTL1RARBLPL
SCHEMBL9485892 0.89 CHKA (0.39) TAAR1MPLL3MBTL1RARBLPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5273680-A A chiral tilted smectic liquid crystal based on terphenyls MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-12-28 US disclosed