SCHEMBL9563808

SCHEMBL9563808

CCCOc1ccc(-c2ccc(CCC)cc2)c(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 2/20 0.38
GABRA1 P14867 5/20 0.36
GABRB2 P47870 5/20 0.36
C3AR1 Q16581 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
ALDH1A1 P00352 2/20 0.35
ALOX5 P09917 1/20 0.35
MPL P40238 1/20 0.35
LMNA P02545 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
S1PR1 P21453 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
TP53 P04637 1/20 0.34
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9563721 0.98 CSNK2A1 (0.37) CSNK2A1GABRA1GABRB2C3AR1FFAR4
SCHEMBL9494738 0.98 CSNK2A1 (0.37) CSNK2A1GABRA1GABRB2C3AR1FFAR4
SCHEMBL19753782 0.93 RARB (0.41) GABRA1GABRB2FFAR4ALDH1A1ALOX5
SCHEMBL15119768 0.93 CNR2 (0.40) ALDH1A1MPLLMNAL3MBTL1S1PR1
SCHEMBL17791137 0.92 RARB (0.40) CSNK2A1GABRA1GABRB2C3AR1FFAR4
SCHEMBL10091128 0.92 CTSL (0.40) CSNK2A1GABRA1GABRB2C3AR1FFAR4
SCHEMBL16803345 0.91 MPL (0.41) CSNK2A1ALDH1A1MPLLMNAS1PR1
SCHEMBL9563933 0.91 S1PR1 (0.42) ALDH1A1MPLLMNAL3MBTL1S1PR1
SCHEMBL20346165 0.91 S1PR1 (0.40) ALDH1A1MPLLMNAL3MBTL1S1PR1
SCHEMBL19753780 0.91 ALDH1A1 (0.39) GABRA1GABRB2FFAR4ALDH1A1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265345-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND APPLICATION OF LIQUID CRYSTAL COMPOSITION BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-08-24 US disclosed
US-20230183572-A1 LIQUID CRYSTAL COMPOSITION WITH GOOD FREQUENCY DEPENDENCE AND LIQUID CRYSTAL DISPLAY ELEMENT SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2023-06-15 US disclosed
US-9938463-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2018-04-10 US disclosed
US-9938463-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2018-04-10 US disclosed
US-20170226419-A1 POLYMERIZABLE-MONOMER-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-08-10 US disclosed
US-20170226419-A1 POLYMERIZABLE-MONOMER-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-08-10 US disclosed
US-20170210989-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2017-07-27 US disclosed
US-20170210989-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2017-07-27 US disclosed
EP-3159393-A1 POLYMERIZABLE-MONOMER-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC Corporation (JP) 2017-04-26 EP disclosed
US-20160075946-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2016-03-17 US disclosed
US-9175221-B2 Nematic liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2015-11-03 US disclosed
US-9175221-B2 Nematic liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2015-11-03 US disclosed
EP-2883937-A1 LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC Corporation (JP) 2015-06-17 EP disclosed
US-20150152331-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2015-06-04 US disclosed
US-20150152331-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2015-06-04 US disclosed
US-5273680-A A chiral tilted smectic liquid crystal based on terphenyls MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-12-28 US disclosed
EP-0329752-A1 FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS MERCK PATENT GmbH (DE) 1989-08-30 EP disclosed
WO-1989002425-A1 FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-03-23 WO disclosed