SCHEMBL956381

SCHEMBL956381

Cc1ccsc1CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5481203 0.78 ALDH1A1 (0.49)
SCHEMBL10445253 0.77
SCHEMBL256017 0.77
SCHEMBL243040 0.75
SCHEMBL5842007 0.75
SCHEMBL3253224 0.75
SCHEMBL3023589 0.75
SCHEMBL4034193 0.75
SCHEMBL5280796 0.75
SCHEMBL1296475 0.75 ALDH1A1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110204556-A (RS)-methoxyl group Cefoxitin preparation method 重庆医药高等专科学校 2019-09-06 CN claimed
EP-0055470-A1 Antiinflammatory 4,5-diaryl-alpha-(polyhalomethyl)-2-thiophenemethanols E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-07-07 EP claimed
CN-119371425-A Nitrogen-containing heterocyclic compound, preparation method and medical application thereof 中国医药研究开发中心有限公司 2025-01-28 CN disclosed
WO-2023151641-A1 HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH BEIGENE , LTD. (KY) 2023-08-17 WO disclosed
US-20230139896-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-05-04 US disclosed
CN-111362986-B Thieno [2,3-d ] pyridazine cyclometalated iridium complex and preparation method thereof 安徽工业大学 2023-04-07 CN disclosed
CN-115667269-A Pyridone-containing fused ring derivative inhibitor, and preparation method and application thereof 上海翰森生物医药科技有限公司 2023-01-31 CN disclosed
CN-111362986-A Thieno [2,3-d ] pyridazine cyclometalated iridium complex and preparation method thereof 安徽工业大学 2020-07-03 CN disclosed
EP-2432776-B1 METHYL SULFANYL PYRIMIDINES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS UNIV LAVAL (CA) 2019-09-11 EP disclosed
US-9321769-B2 Heterocyclic acrylamides and their use as pharmaceuticals FAB PHARMA S.A.S. (FR) 2016-04-26 US disclosed
US-9321769-B2 Heterocyclic acrylamides and their use as pharmaceuticals FAB PHARMA S.A.S. (FR) 2016-04-26 US disclosed
US-4923882-A Novel amine derivatives, salts thereof and an anti-ulcer agent containing the same TOYAMA CHEMICAL CO., LTD. (JP) 1990-05-08 US disclosed
US-4643849-A ANTIULCER, ANTISECRETORY AGENTS TOYAMA CHEMICAL CO., LTD. (JP) 1987-02-17 US disclosed
EP-0032131-B1 5-HALO-PYRIMIDIN-2-ONES, THE SALTS THEREOF, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM NYEGAARD &amp; CO. A/S (NO) 1983-09-21 EP disclosed
US-4399140-A CYTOTOXIC NYEGAARD & CO. A/S (NO) 1983-08-16 US disclosed
EP-0032131-A1 5-Halo-pyrimidin-2-ones, the salts thereof, processes for their preparation and pharmaceutical compositions containing them NYEGAARD &amp; CO. A/S (NO) 1981-07-15 EP disclosed
US-4256878-A THIENYL COMPOUNDS, ANTITUMOR AGENTS HOFFMANN-LA ROCHE INC. (US) 1981-03-17 US disclosed
US-4230872-A ANTITUMOR AGENTS, THIENYL-3,7-DIMETHYLNONA-2,4,6,8-TETRAENE HOFFMANN-LA ROCHE INC. (US) 1980-10-28 US disclosed
US-4116975-A 9-THIENYL-3,7-DIMETHYLNONA-2,4,6,8-TETRAENES, ANTITUMOR HOFFMANN-LA ROCHE INC. (US) 1978-09-26 US disclosed
US-4061656-A ANTITUMOR HOFFMANN-LA ROCHE INC. (US) 1977-12-06 US disclosed