Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | TKT | P29401 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8815622 | 0.81 | ALOX5 (0.44) | ALDH1A1ALOX5RIPK1GSK3BADRA1D | |
| SCHEMBL30954534 | 0.79 | ALOX5 (0.43) | ALDH1A1ALOX5RIPK1GSK3BADRA1D | |
| SCHEMBL6617196 | 0.79 | ALOX5 (0.43) | ALDH1A1ALOX5RIPK1GSK3BADRA1D | |
| SCHEMBL956381 | 0.78 | — | — | |
| SCHEMBL5960013 | 0.78 | ALOX5 (0.42) | ALDH1A1ALOX5RIPK1ADRA1DKDM4E | |
| SCHEMBL19304398 | 0.78 | ALOX5 (0.42) | ALDH1A1ALOX5RIPK1ADRA1DKDM4E | |
| SCHEMBL21142475 | 0.78 | ALOX5 (0.42) | ALDH1A1ALOX5RIPK1ADRA1DKDM4E | |
| SCHEMBL4436694 | 0.78 | ALOX5 (0.42) | ALDH1A1ALOX5RIPK1ADRA1DKDM4E | |
| SCHEMBL6809052 | 0.77 | LTB4R (0.50) | ALDH1A1ALOX5RIPK1GSK3BHSD11B1 | |
| SCHEMBL8572643 | 0.77 | ALOX5 (0.58) | ALDH1A1ALOX5RIPK1GSK3BHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186426-B2 | Prevention of lactic acid bacteria spoilage of beer through use of bacteriocin-containing fermented wort | KRAFT FOODS HOLDINGS, INC. (US) | 2007-03-06 | — | — | US | disclosed |
| US-20020192331-A1 | Prevention of lactic acid bacteria spoilage of beer through use of bacteriocin-containing fermented wort | KRAFT FOODS HOLDINGS, INC. | 2002-12-19 | — | — | US | disclosed |
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| US-6248739-B1 | DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES | PHARMACIA & UPJOHN COMPANY | 2001-06-19 | — | — | US | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |