Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563890 | 1.00 | PPID (0.41) | PPIDKDM4EPOLBKMT2AMAPT | |
| SCHEMBL9563902 | 0.91 | CTBP2 (0.40) | KDM4EPOLBKMT2AMAPTMEN1 | |
| SCHEMBL9563897 | 0.91 | CTBP2 (0.40) | KDM4EPOLBKMT2AMAPTMEN1 | |
| SCHEMBL9564028 | 0.88 | CTBP2 (0.48) | KDM4EPOLBKMT2AMAPTALDH1A1 | |
| SCHEMBL9564036 | 0.88 | CTBP2 (0.48) | KDM4EPOLBKMT2AMAPTALDH1A1 | |
| SCHEMBL9564047 | 0.76 | GAA (0.34) | KDM4EPOLBKMT2AMAPTLMNA | |
| SCHEMBL9563878 | 0.74 | GAA (0.39) | KDM4EPOLBKMT2AMAPTLMNA | |
| SCHEMBL9563874 | 0.74 | GAA (0.39) | KDM4EPOLBKMT2AMAPTLMNA | |
| SCHEMBL9563876 | 0.74 | GAA (0.39) | KDM4EPOLBKMT2AMAPTLMNA | |
| SCHEMBL1332625 | 0.71 | ALDH1A1 (0.68) | PPIDKMT2AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525832-A1 | Substituted 1,2,3- thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1993-02-03 | — | — | EP | disclosed |
| US-4916237-A | Substituted 1,2,3-thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
| US-4803280-A | Substituted 1,2,3-thia-diazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1989-02-07 | — | — | US | disclosed |