Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564036 | 1.00 | CTBP2 (0.48) | CTBP2CYP1A2ALDH1A1KDM4EMAPT | |
| SCHEMBL9563890 | 0.88 | PPID (0.41) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL9563887 | 0.88 | PPID (0.41) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL9563897 | 0.82 | CTBP2 (0.40) | CTBP2KDM4EMAPTPOLBGAA | |
| SCHEMBL9563902 | 0.82 | CTBP2 (0.40) | CTBP2KDM4EMAPTPOLBGAA | |
| SCHEMBL511950 | 0.76 | POLB (0.56) | CTBP2CYP1A2ALDH1A1KDM4EMAPT | |
| SCHEMBL29640755 | 0.76 | POLB (0.56) | CTBP2CYP1A2ALDH1A1KDM4EMAPT | |
| SCHEMBL30172792 | 0.74 | CTBP2 (0.51) | CTBP2CYP1A2ALDH1A1KDM4EMAPT | |
| SCHEMBL4319346 | 0.74 | CTBP2 (0.51) | CTBP2CYP1A2ALDH1A1KDM4EMAPT | |
| SCHEMBL1802183 | 0.74 | ALDH1A1 (0.56) | CYP1A2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525832-A1 | Substituted 1,2,3- thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1993-02-03 | — | — | EP | disclosed |
| US-4916237-A | Substituted 1,2,3-thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
| US-4803280-A | Substituted 1,2,3-thia-diazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1989-02-07 | — | — | US | disclosed |