SCHEMBL9564040

SCHEMBL9564040

NCc1ccc2ccccc2c1S(=O)(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 3/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
CYP2D6 P10635 1/20 0.43
CA2 P00918 2/20 0.39
SLC2A1 P11166 1/20 0.38
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38
PKM P14618 1/20 0.38
RAB9A P51151 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
HSD17B10 Q99714 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
SCN1A P35498 1/20 0.37
SCN2A Q99250 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28228311 0.87 CYP2D6 (0.41) KDM4EALDH1A1GAAMAPTTAAR1
SCHEMBL198197 0.86 CYP2D6 (0.45) ALDH1A1CYP2D6SLC2A1HSD17B10CYP1A2
SCHEMBL30122848 0.86 CYP2D6 (0.45) ALDH1A1CYP2D6SLC2A1HSD17B10CYP1A2
SCHEMBL8773054 0.86 CYP2D6 (0.45) KDM4EALDH1A1CYP2D6CA2SLC2A1
SCHEMBL6336158 0.84 CYP2D6 (0.44) ALDH1A1CYP2D6SLC2A1HSD17B10CYP1A2
SCHEMBL417875 0.84 SLC2A1 (0.45) ALDH1A1CYP2D6SLC2A1HSD17B10CTRB1
SCHEMBL20885747 0.84 PAX8 (0.42) KDM4EALDH1A1GAAMAPTTAAR1
Naphthalene SCHEMBL28184204 0.84 CYP2D6 (0.44) ALDH1A1CYP2D6SLC2A1HSD17B10CYP1A2
Ammonia Solution, Strong SCHEMBL23749153 0.83 SLC2A1 (0.44) KDM4ECYP2D6SLC2A1CTRB1
Formaldehyde SCHEMBL10787861 0.81 SLC2A1 (0.43) CYP2D6SLC2A1CTRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0525572-A2 Reactive dyes BAYER AG (DE) 1993-02-03 EP disclosed
EP-0443165-A1 Reactive dyes BAYER AG (DE) 1991-08-28 EP disclosed