SCHEMBL8773054

SCHEMBL8773054

O=S(=O)(O)c1c(CO)ccc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.45
SLC2A1 P11166 2/20 0.40
TDP1 Q9NUW8 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP2A6 P11509 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CTRB1 P17538 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ERN1 O75460 1/20 0.38
MPL P40238 1/20 0.38
CTRC Q99895 1/20 0.38
CA2 P00918 1/20 0.38
ACP3 P15309 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30122848 0.89 CYP2D6 (0.45) CYP2D6SLC2A1TDP1ALDH1A1CYP2A6
SCHEMBL198197 0.89 CYP2D6 (0.45) CYP2D6SLC2A1TDP1ALDH1A1CYP2A6
SCHEMBL6336158 0.87 CYP2D6 (0.44) CYP2D6SLC2A1TDP1ALDH1A1CYP2A6
Naphthalene SCHEMBL28184204 0.87 CYP2D6 (0.44) CYP2D6SLC2A1TDP1ALDH1A1CYP2A6
SCHEMBL417875 0.87 SLC2A1 (0.45) CYP2D6SLC2A1TDP1ALDH1A1CYP2A6
Ammonia Solution, Strong SCHEMBL23749153 0.86 SLC2A1 (0.44) CYP2D6SLC2A1CTRB1KDM4E
SCHEMBL9564040 0.86 KDM4E (0.43) CYP2D6SLC2A1TDP1ALDH1A1CYP2A6
Formaldehyde SCHEMBL10787861 0.84 SLC2A1 (0.43) CYP2D6SLC2A1CTRB1
SCHEMBL9142087 0.83 CTRC (0.47) CYP2D6TDP1KDM4ECTRCCA2
SCHEMBL9658683 0.83 GPR55 (0.46) CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0383995-B1 Aromatic thermosetting resins and preparation thereof SUMIKIN CHEMICAL (JP) 1997-10-15 EP disclosed
US-5017683-A Organic acid catalyst SUMIKIN CHEMICAL CO., LTD. (JP) 1991-05-21 US disclosed
EP-0383995-A2 Aromatic thermosetting resins and preparation thereof SUMIKIN CHEMICAL CO., LTD. (JP) 1990-08-29 EP disclosed