SCHEMBL9564304

SCHEMBL9564304

COP(=O)(O)OC(C)(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
CYP2C19 P33261 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.35
FDPS P14324 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3817093 0.79 LMNA (0.41) LMNACYP2C19FDPS
SCHEMBL9634584 0.76 BTN3A1 (0.34)
SCHEMBL10435332 0.76
SCHEMBL5013451 0.75 LMNA (0.38) LMNAFDPS
SCHEMBL9564289 0.74
SCHEMBL5968815 0.74 LMNA (0.36) LMNACYP2C19L3MBTL1
SCHEMBL15338706 0.73 LMNA (0.36) LMNAFDPS
SCHEMBL8007500 0.73 FDPS (0.30) FDPS
SCHEMBL18628632 0.72 LMNA (0.33) LMNACYP2C19
SCHEMBL11547903 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0523991-A1 High resiliency polyurethane foams with improved static fatigue ARCO CHEMICAL TECHNOLOGY, INC. (US) 1993-01-20 EP claimed
US-5157056-A Contains phosphorous compounds ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1992-10-20 US claimed
EP-0523991-A1 High resiliency polyurethane foams with improved static fatigue ARCO CHEMICAL TECHNOLOGY, INC. (US) 1993-01-20 EP disclosed
US-5157056-A Contains phosphorous compounds ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1992-10-20 US disclosed