Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564375 | 0.72 | HIF1A (0.43) | NPC1RAB9AMAPK1EPHX2HPGD | |
| SCHEMBL9564352 | 0.70 | CYP2C19 (0.44) | RAB9ASMN1; SMN2TP53MAPK1MAPK14 | |
| SCHEMBL15104516 | 0.61 | NOTUM (0.60) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL8245050 | 0.60 | PTPRZ1 (0.55) | EPHX2ALDH1A1PTGS1PTGS2PTPN1 | |
| SCHEMBL13981960 | 0.60 | TDP1 (0.47) | NPC1RAB9ASMN1; SMN2TP53HSD17B10 | |
| SCHEMBL24590456 | 0.60 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2TP53MAPK1 | |
| SCHEMBL15157652 | 0.58 | SLC6A4 (0.61) | EPHX2POLBALDH1A1PTPN1PTPRZ1 | |
| SCHEMBL10869005 | 0.58 | SMN1; SMN2 (0.55) | NPC1RAB9ASMN1; SMN2TP53HSD17B10 | |
| SCHEMBL9205402 | 0.58 | PTPRZ1 (0.47) | EPHX2ALDH1A1ATMPTPN1PTPRZ1 | |
| SCHEMBL22795275 | 0.57 | TDP1 (0.52) | SMN1; SMN2TP53ALDH1A1PTPN1PTPRZ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |