Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 2/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564352 | 0.86 | CYP2C19 (0.44) | CYP2C9CYP2C19CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL9564383 | 0.79 | CYP2C9 (0.45) | CYP2C9CYP2C19CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL15686704 | 0.78 | RET (0.45) | CYP2C9CYP2C19CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL13363881 | 0.76 | CYP2A6 (0.48) | CYP2C9CYP2C19CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL26551519 | 0.74 | FLT3 (0.62) | FLT3CYP3A4CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL4318440 | 0.74 | CYP3A4 (0.62) | CYP2C9CYP2C19CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL8378894 | 0.72 | CYP2A6 (0.48) | CYP2C9CYP2C19CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL9404417 | 0.72 | CYP2C19 (0.47) | CYP2C9CYP2C19CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL12611843 | 0.72 | CHRNB2 (0.58) | ALDH1A1CHRNB2CHRNA5CHRNA4SMN1; SMN2 | |
| SCHEMBL26547900 | 0.72 | CHEK1 (0.55) | FLT3CYP2C9CYP2C19CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |