Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564421 | 1.00 | KDM4E (0.49) | KDM4ELMNAL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL29601190 | 0.79 | KMT2A (0.55) | KDM4ELMNAL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL11051347 | 0.79 | KMT2A (0.55) | KDM4ELMNAL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL9564366 | 0.75 | GAA (0.50) | KDM4ELMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9564371 | 0.75 | GAA (0.50) | KDM4ELMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9564388 | 0.74 | MAPT (0.52) | KDM4EHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2692097 | 0.74 | MAPT (0.52) | KDM4EHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2692103 | 0.74 | MAPT (0.52) | KDM4EHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2516053 | 0.74 | KDM4E (0.69) | KDM4ELMNAL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL27039700 | 0.74 | EGFR (0.52) | KDM4ELMNASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |