Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MITF | O75030 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564468 | 1.00 | MAPT (0.45) | MAPTLMNAVCAM1POLBNPSR1 | |
| SCHEMBL10864550 | 0.92 | MAPT (0.45) | MAPTLMNAVCAM1POLBNPSR1 | |
| SCHEMBL1005272 | 0.85 | MAPT (0.43) | MAPTLMNAVCAM1POLBNPSR1 | |
| SCHEMBL6482749 | 0.85 | MAPT (0.43) | MAPTLMNAVCAM1POLBNPSR1 | |
| SCHEMBL9720579 | 0.84 | GAA (0.42) | MAPTLMNANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL9211517 | 0.84 | GAA (0.42) | MAPTLMNANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL9562462 | 0.84 | GAA (0.42) | MAPTLMNANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL29754269 | 0.84 | GAA (0.42) | MAPTLMNANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL5256942 | 0.82 | GAA (0.48) | MAPTLMNAPOLBNPSR1HTT | |
| SCHEMBL10592860 | 0.82 | GAA (0.48) | MAPTLMNAPOLBNPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |