Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103967 | 0.80 | TDP1 (0.51) | TDP1HTTALDH1A1NPC1RAB9A | |
| SCHEMBL3363432 | 0.75 | NPC1 (0.50) | TDP1HTTALDH1A1NPC1RAB9A | |
| SCHEMBL7354309 | 0.73 | CYP1A2 (0.46) | TDP1HTTALDH1A1NPC1RAB9A | |
| SCHEMBL7347904 | 0.73 | GUCY1B2 (0.51) | TDP1HTTALDH1A1CYP3A4NPC1 | |
| SCHEMBL7051529 | 0.73 | TDP1 (0.50) | TDP1ALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL3462835 | 0.73 | TDP1 (1.00) | TDP1HTTALDH1A1CYP3A4MEN1 | |
| SCHEMBL269845 | 0.73 | TDP1 (1.00) | TDP1HTTALDH1A1CYP3A4MEN1 | |
| Hydrochloric Acid SCHEMBL21772081 | 0.71 | TDP1 (0.96) | TDP1HTTALDH1A1CYP3A4MEN1 | |
| Ammonia Solution, Strong SCHEMBL10880861 | 0.71 | TDP1 (0.96) | TDP1HTTALDH1A1CYP3A4MEN1 | |
| SCHEMBL222283 | 0.71 | HTT (1.00) | TDP1HTTALDH1A1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542609-A1 | 3-sulfonylamino-2-(1H)-quinolinones and 7-aza derivatives as excitatory amino acids antagonists | ADIR ET COMPAGNIE (FR) | 1993-05-19 | — | — | EP | disclosed |