Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.50 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.50 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.50 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.50 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.50 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.50 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354309 | 0.89 | CYP1A2 (0.46) | TDP1CYP1A2ALDH1A1POLBTXNRD1 | |
| SCHEMBL7347904 | 0.85 | GUCY1B2 (0.51) | TDP1CYP1A2ALDH1A1POLBTXNRD1 | |
| SCHEMBL1770090 | 0.80 | SMN1; SMN2 (0.56) | TDP1CYP1A2ALDH1A1POLBTXNRD1 | |
| SCHEMBL9564530 | 0.80 | TDP1 (0.56) | TDP1ALDH1A1POLBTXNRD1TXNRD3 | |
| SCHEMBL15197892 | 0.80 | CYP1A2 (0.58) | TDP1CYP1A2ALDH1A1TXNRD1TXNRD3 | |
| SCHEMBL1259529 | 0.78 | GUCY1B2 (0.59) | TDP1CYP1A2ALDH1A1POLBTXNRD1 | |
| SCHEMBL3563953 | 0.78 | RAB9A (0.52) | TDP1CYP1A2ALDH1A1TXNRD1TXNRD3 | |
| SCHEMBL30891215 | 0.78 | RAB9A (0.52) | TDP1CYP1A2ALDH1A1TXNRD1TXNRD3 | |
| SCHEMBL31399941 | 0.77 | CYP1A2 (0.55) | TDP1CYP1A2ALDH1A1TXNRD1TXNRD3 | |
| SCHEMBL10928797 | 0.77 | CYP1A2 (0.55) | TDP1CYP1A2ALDH1A1POLBTXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1137886-C | 2,3-dioxo-1,2,3,4-tetrahydro-quinoyxalinyl derivatives | ��˹��ŵ�� | 2004-02-11 | — | — | CN | disclosed |
| US-20030207886-A1 | Preparation containing quinoxaline derivatives | MERCK PATENT GMBH (DE) | 2003-11-06 | — | — | US | disclosed |
| CN-1092202-C | Subsd. aminoalkane phosphonic acids | NOVARTIS AG (CH) | 2002-10-09 | — | — | CN | disclosed |
| CN-1234037-A | Subsd. aminoalkane phosphonic acids | NOVARTIS AG (CH) | 1999-11-03 | — | — | CN | disclosed |
| CN-1193968-A | 2,3-dioxo-1,2,3,4-tetrahydro-quinoyxalinyl derivatives | NOVARTIS AG (CH) | 1998-09-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207886-A1 | Preparation containing quinoxaline derivatives | CUTA, XPA, NQO2 | TDP1 1899/4885CYP1A2 226/4885ALDH1A1 1898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.