Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564526 | 0.82 | GRIA1 (0.66) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9564553 | 0.80 | BRD4 (0.53) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11601172 | 0.77 | DAO (0.56) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL829211 | 0.73 | DAO (0.60) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4388117 | 0.73 | DAO (0.64) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3792756 | 0.70 | KIF11 (0.50) | POLBTSHR | |
| SCHEMBL830417 | 0.70 | DAO (0.55) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2463866 | 0.69 | DAO (0.64) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31378780 | 0.69 | DAO (0.64) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16767847 | 0.69 | DAO (1.00) | DAOGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542609-A1 | 3-sulfonylamino-2-(1H)-quinolinones and 7-aza derivatives as excitatory amino acids antagonists | ADIR ET COMPAGNIE (FR) | 1993-05-19 | — | — | EP | disclosed |