Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | DDO | Q99489 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564535 | 0.81 | STK33 (0.55) | BRD4KDM4EHSD17B10DAODDO | |
| SCHEMBL9564541 | 0.80 | GRIA1 (0.63) | BRD4KDM4EHSD17B10CYP1A2DAO | |
| SCHEMBL9564534 | 0.80 | DAO (0.53) | KDM4EHSD17B10CYP1A2DAOGRIN2D | |
| SCHEMBL12909532 | 0.80 | BRD4 (0.59) | BRD4KDM4EHSD17B10CYP1A2DAO | |
| SCHEMBL5268525 | 0.78 | CA2 (0.47) | BRD4KDM4EHSD17B10CYP1A2DAO | |
| SCHEMBL16627809 | 0.76 | BRD4 (0.51) | BRD4KDM4EHSD17B10CYP1A2DAO | |
| SCHEMBL9564525 | 0.76 | BRD4 (0.55) | BRD4ALDH1A1CDK5CDK5R1 | |
| SCHEMBL12890517 | 0.75 | BRD4 (0.54) | BRD4KDM4EHSD17B10CYP1A2DAO | |
| SCHEMBL16627856 | 0.75 | BRD4 (0.54) | BRD4KDM4EHSD17B10CYP1A2DAO | |
| SCHEMBL29253640 | 0.74 | DAO (0.53) | BRD4KDM4EHSD17B10CYP1A2DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542609-A1 | 3-sulfonylamino-2-(1H)-quinolinones and 7-aza derivatives as excitatory amino acids antagonists | ADIR ET COMPAGNIE (FR) | 1993-05-19 | — | — | EP | disclosed |