Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.66 |
| ▸ | LDHA | P00338 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12706131 | 1.00 | CYP1A2 (1.00) | CYP1A2CYP2D6CYP2C19SLC6A4LDHA | |
| SCHEMBL8066335 | 0.91 | CYP1A2 (0.83) | CYP1A2CYP2D6CYP2C19SLC6A4LDHA | |
| SCHEMBL8056897 | 0.91 | CYP1A2 (0.83) | CYP1A2CYP2D6CYP2C19SLC6A4LDHA | |
| SCHEMBL7039221 | 0.91 | CYP1A2 (0.83) | CYP1A2CYP2D6CYP2C19SLC6A4LDHA | |
| SCHEMBL9201706 | 0.91 | CYP1A2 (0.83) | CYP1A2CYP2D6CYP2C19SLC6A4LDHA | |
| SCHEMBL5680007 | 0.91 | CYP1A2 (0.83) | CYP1A2CYP2D6CYP2C19SLC6A4LDHA | |
| SCHEMBL2368100 | 0.91 | CYP1A2 (0.83) | CYP1A2CYP2D6CYP2C19SLC6A4LDHA | |
| SCHEMBL28542133 | 0.86 | CYP1A2 (0.73) | CYP1A2CYP2D6CYP2C19SLC6A4LDHA | |
| SCHEMBL656814 | 0.81 | SLC6A4 (0.73) | CYP1A2CYP2D6CYP2C19SLC6A4LDHA | |
| SCHEMBL7528408 | 0.81 | SLC6A4 (0.73) | CYP1A2CYP2D6CYP2C19SLC6A4LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5279311-A | — | — | None | — | — | JP | disclosed |
| WO-2024235225-A1 | SUBSTITUTED PYRIMIDINE-FUSED RING INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2024-11-21 | — | — | WO | disclosed |
| CN-118302425-A | IRAK4 inhibitors and uses thereof | 武汉人福创新药物研发中心有限公司 | 2024-07-05 | — | — | CN | disclosed |
| US-20240150346-A1 | CLASS OF HETEROAROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | INNOVSTONE THERAPEUTICS LIMITED (CN) | 2024-05-09 | — | — | US | disclosed |
| CN-117736210-A | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-3872061-B1 | 1-PHENYL-2-PHENYLETHANE DERIVATIVE | KAO CORP (JP) | 2023-12-27 | — | — | EP | disclosed |
| CN-114805341-B | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-116710452-A | 4-amino-3- (4-phenoxyphenyl) -1, 3-dihydro-2H-imidazo [4,5-C ] pyridin-2-one derivatives and salts thereof | 建新公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116390925-A | AMPK activator | 卡尔优普公司 | 2023-07-04 | — | — | CN | disclosed |
| US-11453632-B2 | 1-phenyl-2-phenylethane derivative | KAO CORPORATION (JP) | 2022-09-27 | — | — | US | disclosed |
| US-11453632-B2 | 1-phenyl-2-phenylethane derivative | KAO CORPORATION (JP) | 2022-09-27 | — | — | US | disclosed |
| CN-115023427-A | Pyrazolotriazines | 拜耳公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-114805341-A | Aromatic heterocyclic compounds and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-112912363-B | 1-phenyl-2-phenylethane derivatives | 花王株式会社 | 2022-06-03 | — | — | CN | disclosed |
| US-20220009869-A1 | 1-PHENYL-2-PHENYLETHANE DERIVATIVE | KAO CORPORATION (JP) | 2022-01-13 | — | — | US | disclosed |
| US-20220009869-A1 | 1-PHENYL-2-PHENYLETHANE DERIVATIVE | KAO CORPORATION (JP) | 2022-01-13 | — | — | US | disclosed |
| WO-2020085373-A1 | 1-PHENYL-2-PHENYLETHANE DERIVATIVE | 花王株式会社 | 2020-04-30 | — | — | WO | disclosed |
| JP-H05279311-A | OXIME DERIVATIVE AND ITS PRODUCTION | SUMITOMO CHEM CO LTD | 1993-10-26 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240150346-A1 | CLASS OF HETEROAROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | TLR7, TLR1, TLR8 | CYP1A2 495/4885CYP2D6 677/4885CYP2C19 935/4885 |
| US-20220009869-A1 | 1-PHENYL-2-PHENYLETHANE DERIVATIVE | ESR2, GPER1, ESR1 | CYP1A2 405/4885CYP2D6 448/4885CYP2C19 889/4885 |
| US-11453632-B2 | 1-phenyl-2-phenylethane derivative | ESR2, GPER1, ESR1 | CYP1A2 405/4885CYP2D6 448/4885CYP2C19 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.