Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 5/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 7/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565002 | 1.00 | GRM4 (0.43) | GRM4ABCC9GRM5KDM4EGAA | |
| SCHEMBL9564998 | 1.00 | GRM4 (0.43) | GRM4ABCC9GRM5KDM4EGAA | |
| SCHEMBL9564993 | 0.88 | GRM4 (0.47) | GRM4ABCC9GRM5KDM4EGAA | |
| SCHEMBL9564991 | 0.88 | GRM4 (0.47) | GRM4ABCC9GRM5KDM4EGAA | |
| SCHEMBL9564992 | 0.88 | GRM4 (0.47) | GRM4ABCC9GRM5KDM4EGAA | |
| SCHEMBL8338039 | 0.74 | ABCC9 (0.69) | ABCC9 | |
| SCHEMBL8338045 | 0.74 | ABCC9 (0.69) | ABCC9 | |
| SCHEMBL8338034 | 0.74 | ABCC9 (0.69) | ABCC9 | |
| SCHEMBL9565138 | 0.73 | ABCC9 (0.46) | ABCC9KDM4EAR | |
| SCHEMBL9565140 | 0.73 | ABCC9 (0.46) | ABCC9KDM4EAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525768-A1 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1993-02-03 | — | — | EP | disclosed |