SCHEMBL9565140

SCHEMBL9565140

CC(=O)NC1c2cc(C#N)ccc2C(=O)C(C)(C)C1O

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ABCC9 O60706 10/20 0.46
AR P10275 1/20 0.43
KDM4E B2RXH2 1/20 0.40
ABCB1 P08183 6/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9565139 1.00 ABCC9 (0.46) ABCC9ARKDM4EABCB1
SCHEMBL9565138 1.00 ABCC9 (0.46) ABCC9ARKDM4EABCB1
SCHEMBL9565101 0.87 ABCC9 (0.40) ABCC9ARKDM4EABCB1
SCHEMBL9565105 0.87 ABCC9 (0.40) ABCC9ARKDM4EABCB1
SCHEMBL9565077 0.86 ABCC9 (0.54) ABCC9ABCB1
SCHEMBL9565081 0.86 ABCC9 (0.54) ABCC9ABCB1
SCHEMBL9565083 0.86 ABCC9 (0.54) ABCC9ABCB1
SCHEMBL9565141 0.84 ABCC9 (0.53) ABCC9KDM4EABCB1
SCHEMBL9565137 0.84 ABCC9 (0.53) ABCC9KDM4EABCB1
SCHEMBL9565145 0.84 ABCC9 (0.53) ABCC9KDM4EABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0525768-A1 Tetralones with pharmacological activity J. URIACH & CIA. S.A. (ES) 1993-02-03 EP disclosed