Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 9/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | GAK | O14976 | 1/20 | 0.38 |
| ▸ | STK16 | O75716 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.38 |
| ▸ | STK3 | Q13188 | 1/20 | 0.38 |
| ▸ | STK11 | Q15831 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565054 | 1.00 | ABCC9 (0.49) | ABCC9CYP11B1CYP11B2NAMPTGAK | |
| SCHEMBL9565050 | 1.00 | ABCC9 (0.49) | ABCC9CYP11B1CYP11B2NAMPTGAK | |
| SCHEMBL9565137 | 0.88 | ABCC9 (0.53) | ABCC9NAMPT | |
| SCHEMBL9565141 | 0.88 | ABCC9 (0.53) | ABCC9NAMPT | |
| SCHEMBL9565145 | 0.88 | ABCC9 (0.53) | ABCC9NAMPT | |
| SCHEMBL9565083 | 0.88 | ABCC9 (0.54) | ABCC9KMT2A | |
| SCHEMBL9565081 | 0.88 | ABCC9 (0.54) | ABCC9KMT2A | |
| SCHEMBL9565077 | 0.88 | ABCC9 (0.54) | ABCC9KMT2A | |
| SCHEMBL9564992 | 0.81 | GRM4 (0.47) | ABCC9KMT2A | |
| SCHEMBL9564993 | 0.81 | GRM4 (0.47) | ABCC9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525768-A1 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1993-02-03 | — | — | EP | disclosed |