Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 9/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565141 | 1.00 | ABCC9 (0.53) | ABCC9ROCK2KDM4EGAAALK | |
| SCHEMBL9565137 | 1.00 | ABCC9 (0.53) | ABCC9ROCK2KDM4EGAAALK | |
| SCHEMBL9565083 | 0.89 | ABCC9 (0.54) | ABCC9ABCB1 | |
| SCHEMBL9565081 | 0.89 | ABCC9 (0.54) | ABCC9ABCB1 | |
| SCHEMBL9565077 | 0.89 | ABCC9 (0.54) | ABCC9ABCB1 | |
| SCHEMBL9565050 | 0.88 | ABCC9 (0.49) | ABCC9NAMPT | |
| SCHEMBL9565054 | 0.88 | ABCC9 (0.49) | ABCC9NAMPT | |
| SCHEMBL9565046 | 0.88 | ABCC9 (0.49) | ABCC9NAMPT | |
| SCHEMBL9565095 | 0.85 | ABCC9 (0.53) | ABCC9GAAALKEGLN1 | |
| SCHEMBL9565099 | 0.85 | ABCC9 (0.53) | ABCC9GAAALKEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525768-A1 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1993-02-03 | — | — | EP | disclosed |