Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866300 | 0.87 | MAPT (0.34) | KCNH2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10506487 | 0.81 | SSTR5 (0.46) | KCNH2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9564954 | 0.79 | SSTR5 (0.47) | KCNH2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9564906 | 0.79 | SSTR5 (0.39) | KCNH2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9564789 | 0.76 | NR4A2 (0.42) | KCNH2MAPTALDH1A1MEN1KMT2A | |
| Water SCHEMBL9564807 | 0.75 | NR4A2 (0.42) | KCNH2MAPTALDH1A1MEN1KMT2A | |
| Water SCHEMBL9564806 | 0.75 | NR4A2 (0.42) | KCNH2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10622081 | 0.74 | ALDH1A1 (0.36) | KCNH2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10509052 | 0.73 | SSTR5 (0.51) | KCNH2MAPTMEN1KMT2AGAA | |
| SCHEMBL1152440 | 0.73 | HPGD (0.38) | KCNH2MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258380-A | Antiallergens, antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-11-02 | — | — | US | disclosed |