Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564838 | 0.90 | SSTR5 (0.43) | SSTR5KCNH2NR4A2CYP1A2CYP2D6 | |
| SCHEMBL9564808 | 0.87 | HTR2A (0.38) | SSTR5KCNH2NR4A2CYP1A2CYP2D6 | |
| SCHEMBL9565012 | 0.85 | SSTR5 (0.39) | SSTR5KCNH2NR4A2CYP1A2CYP2D6 | |
| SCHEMBL9564929 | 0.84 | SSTR5 (0.57) | SSTR5KCNH2NR4A2CYP1A2CYP2D6 | |
| SCHEMBL9564789 | 0.80 | NR4A2 (0.42) | KCNH2NR4A2CYP1A2CYP2D6MEN1 | |
| SCHEMBL9565084 | 0.79 | KCNH2 (0.36) | SSTR5KCNH2MEN1KMT2AMAPT | |
| SCHEMBL9565053 | 0.79 | KCNH2 (0.57) | SSTR5KCNH2NR4A2CYP1A2CYP2D6 | |
| Water SCHEMBL9564806 | 0.79 | NR4A2 (0.42) | KCNH2NR4A2CYP1A2CYP2D6MEN1 | |
| Water SCHEMBL9564807 | 0.79 | NR4A2 (0.42) | KCNH2NR4A2CYP1A2CYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL9564793 | 0.77 | ADRA1D (0.41) | MAPTALDH1A1USP2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258380-A | Antiallergens, antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-11-02 | — | — | US | disclosed |
| US-5041448-A | Antiallergens | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-08-20 | — | — | US | disclosed |
| EP-0206415-A2 | (4-Piperidinylmethyl and -hetero)purines | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-12-30 | — | — | EP | disclosed |