Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588183 | 1.00 | ABCC9 (0.40) | ABCC9KDM4EABCC8KCNJ11KCNJ8 | |
| SCHEMBL9032326 | 0.79 | KDM4E (0.39) | ABCC9KDM4EABCC8KCNJ11KCNJ8 | |
| SCHEMBL9032334 | 0.79 | KDM4E (0.39) | ABCC9KDM4EABCC8KCNJ11KCNJ8 | |
| SCHEMBL9032328 | 0.79 | KDM4E (0.39) | ABCC9KDM4EABCC8KCNJ11KCNJ8 | |
| SCHEMBL9565138 | 0.79 | ABCC9 (0.46) | ABCC9KDM4EABCB1 | |
| SCHEMBL9565140 | 0.79 | ABCC9 (0.46) | ABCC9KDM4EABCB1 | |
| SCHEMBL9565139 | 0.79 | ABCC9 (0.46) | ABCC9KDM4EABCB1 | |
| SCHEMBL9587883 | 0.78 | CA1 (0.41) | KCNE1KCNQ1KDM1A | |
| SCHEMBL9703829 | 0.78 | CA1 (0.41) | KCNE1KCNQ1KDM1A | |
| SCHEMBL9588047 | 0.78 | CA1 (0.41) | KDM4ECYP1A2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525768-A1 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1993-02-03 | — | — | EP | disclosed |
| EP-0489300-A2 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1992-06-10 | — | — | EP | disclosed |