Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAB2 | O43741 | 1/20 | 0.66 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.66 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.66 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.66 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.66 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.66 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.46 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905007 | 0.88 | PRKAB2 (0.67) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL29721489 | 0.87 | PRKAB2 (0.70) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL27209464 | 0.87 | PRKAB2 (0.70) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL23982458 | 0.85 | PRKAB2 (0.68) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL20419031 | 0.85 | PRKAB2 (0.68) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL10688239 | 0.84 | PRKAB2 (0.67) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL31685604 | 0.84 | PRKAB2 (0.71) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL5982554 | 0.82 | PRMT6 (0.62) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL20626256 | 0.82 | PRKAB2 (0.65) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL20626260 | 0.82 | PRKAB2 (0.65) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567841-A2 | Fluorescently marked compounds, their preparation and use | MERCK PATENT GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |